Firma de Licencia de Plataforma Estratégica
MaxCyte and Lion TCR form Partnership to Support Global Expansion of Lion TCR's
TCR-T Cell Pipeline
Lion TCR to use MaxCyte's Flow Electroporation® technology and ExPERT? platform to develop and scale TCR-T cell therapies for solid tumors and viral-related diseases.
ROCKVILLE, MD, and SINGAPUR, Enero 3, 2024 - MaxCyte, Inc., (Nasdaq: MXCT; LSE: MXCT), a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics and innovative bioprocessing applicationsy León TCR, an Asia-based, clinical-stage biotechnology company focused on the development of T cell receptor (TCR)-T cell therapies for solid tumors and life-threatening viral infections anunció hoy the signing of a strategic platform license (SPL). This partnership will enhance MaxCyte's presence in Asia, with anticipated expansion into the US and European markets.
Under the terms of the agreement, Lion TCR obtains worldwide non-exclusive clinical and commercial rights to use MaxCyte's Flow Electroporation® technology and ExPERT? platform. In return, MaxCyte is entitled to receive annual license fees and program-related revenue.
"We are thrilled to partner with Lion TCR to support the development of their TCR-T cell therapies for hepatocellular carcinoma and life-threatening viral infections," said Maher Masoud, presidente y director ejecutivo de MaxCyte. "Through this important partnership, we will be able to help provide the opportunity for patients in Asia (and ultimately patients worldwide) to benefit from these innovative mRNA-based TCR-T cell treatments and continue supporting the development of new therapies for patients with solid tumors."
Lion's proprietary TCR-T cell therapy platform is supported by robust research, in collaboration with renowned laboratories, in the areas of autologous T cells and 'off-the-shelf' technologies. De la empresa TCR-T cell therapy harnesses the patient's own immune system to fight against viral infections and cancers. The company is conducting ongoing clinical trials against hepatocellular carcinoma to evaluate the safety and efficacy of its TCR-T cells. Lion has engineered Hepatitis B virus (HBV)-specific T cells to recognize HBV-expressing tumor cells and achieve targeted killing, which is key as HBV is a major cause of hepatocellular carcinoma.
"At Lion TCR, we aspire to be the world's leader in the field of mRNA-based TCR-T therapeutics through the technological advancement and development of adoptive T cell therapy products for cancers and cancer-causing infectious diseases," said CEO, Xiaoming Peng PhD, MBA. "We are honored to have MaxCyte as a partner and leverage their large-scale flow electroporation technology to support our development of novel therapeutics to benefit patients suffering from these devastating diseases."
MaxCyte's ExPERT? instrument portfolio is the next generation of leading, clinically-validated electroporation technology for complex and scalable cell engineering. By delivering high transfection efficiency, seamless scalability and enhanced functionality, the ExPERT? platform delivers the high-end performance essential to enabling the next wave of biological and cellular therapeutics. Lion TCR is MaxCyte's 24th strategic partnership overall, each of which generates pre-commercial milestone revenue and the vast majority of which include sales-based payments.
Acerca de MaxCyte
En MaxCyte, buscamos la excelencia en la ingeniería celular para maximizar el potencial de las células para mejorar la vida de los pacientes. Hemos dedicado más de 20 años a perfeccionar nuestra experiencia creando las mejores plataformas, perfeccionando el arte del flujo de trabajo de transfección y aventurándonos más allá de los procesos actuales para innovar en las soluciones del mañana. ¿Nuestro EXPERTO? plataforma, que se basa en nuestra electroporación de flujo® technology, has been designed to support the rapidly expanding cell therapy market and can be utilized across the continuum of the high-growth cell therapy sector, from discovery and development through commercialization of next-generation, cell-based medicines. The ExPERT family of products includes: four instruments, the ATx?, STx?, GTx? and VLx ?; a portfolio of proprietary related processing assemblies or disposables; and software protocols, all supported by a robust worldwide intellectual property portfolio. By providing our partners with the right technology, as well as scientific, technical and regulatory support, we aim to guide them on their journey to transform human health. Learn more at maxcyte.com y síguenos en Twitter y Etiqueta LinkedIn.
About Lion TCR Pte Ltd
Lion TCR, a clinical stage biotech spun off from Singapore's A*STAR, specializes in engineered T Cell Receptor (TCR) T cell therapies for infectious diseases and associated cancers, particularly HBV-related hepatocellular carcinoma (HCC). Lion TCR have secured FDA IND approval for a Phase 1b/2 trial - the world's first FDA-approved international multi-center trial for its HBV TCR-T therapy (LioCyx-M004) against HCC. Additionally, LioCyx-M004 has received dual Fast Track and Orphan Drug Designations from the FDA. Lion TCR's groundbreaking approach involves utilizing mRNA to encode HBV-specific TCR in patients' T cells, enabling the targeting of HBV epitopes expressed in liver cancer cells. Positive clinical trial outcomes attest to its efficacy. Building on their mRNA technology and AI-enabled TCR discovery platforms, Lion TCR extends its focus to solid tumors, offering personalized cell therapy and 'off-the-shelf' solutions. This positions Lion TCR to develop a robust pipeline for diverse solid cancers and chronic viral diseases. Learn more at liontcr.com.
Contactos de MaxCyte:
Asesor de IR de EE. UU.
Grupo Gilmartin
David Deuchler
+1 415-937-5400
Relaciones con los medios de EE. UU.
Colaboración sísmica de espectro
Valeria Enes
+1 408-497-8568
Consejero Designado y Sociedad Conjunta Broker
panmure gordon
Emma Earl/Freddy Crossley
Corretaje corporativo
Rupert Dearden
44 0 20 7886 2500
Asesor de RI del Reino Unido
Consejo ICR
Mary Jane Elliott
chris galés
44 0 203 709 5700
Lion TCR Contacts:
2 Tukang Innovation Grove
# 09-04
Singapur 618305
+65 68130738
RNS puede usar su dirección IP para confirmar el cumplimiento de los términos y condiciones, para analizar cómo interactúa con la información contenida en esta comunicación y para compartir dicho análisis de forma anónima con otros como parte de nuestros servicios comerciales. Para obtener más información sobre cómo RNS y la Bolsa de Valores de Londres utilizan los datos personales que nos proporciona, consulte nuestra Política de privacidad.